Platform: Wii
Emulator: Dolphin 3.5
Settings:

Graphics
Backend: Direct3d9
Fullscreen Resolution: 1920x1080
Aspect Ratio: Force 16:9
Use Fullscreen Enabled

Enhancements
Internal Resolution: Auto (Window Size)
Anisotropic 16x

DSP Audio
Audio Backend: xaudio2

Xbox360 controller for Classic Controller

PC Specs:
Asus Rampage Formula
Intel Core 2 Quad Q9450 3,4GHz
8 GBytes DDR2 1020MHz
Radeon HD 6950 2GBytes GDDR5