Bio Hazard Battle review. Classic Game Room reviews BIO HAZARD BATTLE for Sega Mega Drive from 1992. Bio Hazard Battle for the MD (or Sega Genesis) is a side scrolling 2D space ship shooter where you pilot fish space ship things against waves of oddities shooting at you. Biohazard Battle is known for its bass heavy, deep soundtrack with thumping early 90's beats and wild synthesizers. BioHazard Battle is from Sega and remains a fun and playable horizontally scrolling shooter with simple controls and a fun variety of power ups to collect and unleash on enemies. Choose from one of four space ships (alien things) each with their own weapon set and speeds. CGR Bio Hazard Battle video review features BioHazard Battle gameplay recorded from Sega Genesis / Sega Mega Drive.